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Review of Organism Density and Bacteriologic Conversion of Sputum among Tuberculosis Patients

Identifieur interne : 000025 ( Main/Exploration ); précédent : 000024; suivant : 000026

Review of Organism Density and Bacteriologic Conversion of Sputum among Tuberculosis Patients

Auteurs : Francis Adjei Osei [Ghana] ; Anthony Enimil [Ghana] ; Daniel Ansong [Ghana] ; Dennis Odai Laryea [Ghana] ; Nicholas Karikari Mensah [Ghana] ; Evans Xorse Amuzu [Ghana] ; Ebenezer Opambour Agyemang [Ghana] ; Phans Oduro Sarpong [Ghana] ; Isaac Nyanor [Ghana] ; Denis Dekugmen Yar [Ghana]

Source :

RBID : PMC:5525070

Abstract

Objective

This study sought to describe the trend of sputum organism density and the rate of bacteriological conversion among smear positive TB patients assessing care at the Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana.

Methods

We conducted a retrospective patient folder review from January 2013 to March 2016 at the KATH, a tertiary hospital in Ghana. The data was entered into Microsoft Access database and exported into STATA for analysis. We applied basic descriptive statistics to study variables. Sputum conversion rate (SCR) was estimated using the number of negative tests recorded over a period (numerator) and the number of patients reported in the same period (denominator) and expressed as a percentage.

Results

A total of 278 patient records with sputum smear positive at onset were studied. Before treatment sputum density detected in smear microscopy was as follows: 1 acid-fast bacillus (+) (n = 114), scanty (n = 19), ++ (n = 67), and +++ (n = 78). We recorded sputum conversion rate of 80.90%, 94.56%, and 98.31% in the intensive, continuation, and completion phases, respectively.

Conclusion

This study has shown an increasing trend in sputum conversion of smear positive pulmonary tuberculosis and an increasing trend in loss to follow-ups among tuberculosis patients on treatment.


Url:
DOI: 10.1155/2017/7052583
PubMed: 28781995
PubMed Central: 5525070


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<name sortKey="Agyemang, Ebenezer Opambour" sort="Agyemang, Ebenezer Opambour" uniqKey="Agyemang E" first="Ebenezer Opambour" last="Agyemang">Ebenezer Opambour Agyemang</name>
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<name sortKey="Dekugmen Yar, Denis" sort="Dekugmen Yar, Denis" uniqKey="Dekugmen Yar D" first="Denis" last="Dekugmen Yar">Denis Dekugmen Yar</name>
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<title>Objective</title>
<p> This study sought to describe the trend of sputum organism density and the rate of bacteriological conversion among smear positive TB patients assessing care at the Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana.</p>
</sec>
<sec>
<title> Methods</title>
<p> We conducted a retrospective patient folder review from January 2013 to March 2016 at the KATH, a tertiary hospital in Ghana. The data was entered into Microsoft Access database and exported into STATA for analysis. We applied basic descriptive statistics to study variables. Sputum conversion rate (SCR) was estimated using the number of negative tests recorded over a period (numerator) and the number of patients reported in the same period (denominator) and expressed as a percentage.</p>
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<p> A total of 278 patient records with sputum smear positive at onset were studied. Before treatment sputum density detected in smear microscopy was as follows: 1 acid-fast bacillus (+) (
<italic>n</italic>
= 114), scanty (
<italic>n</italic>
= 19), ++ (
<italic>n</italic>
= 67), and +++ (
<italic>n</italic>
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<p> This study has shown an increasing trend in sputum conversion of smear positive pulmonary tuberculosis and an increasing trend in loss to follow-ups among tuberculosis patients on treatment.</p>
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<name sortKey="Sia, I G" uniqKey="Sia I">I. G. Sia</name>
</author>
<author>
<name sortKey="Wieland, M L" uniqKey="Wieland M">M. L. Wieland</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Feng Zeng, Z" uniqKey="Feng Zeng Z">Z. Feng-zeng</name>
</author>
<author>
<name sortKey="Levy, M H" uniqKey="Levy M">M. H. Levy</name>
</author>
<author>
<name sortKey="Sumin, W" uniqKey="Sumin W">W. Sumin</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Rieder, H L" uniqKey="Rieder H">H. L. Rieder</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Shu, C C" uniqKey="Shu C">C.-C. Shu</name>
</author>
<author>
<name sortKey="Wang, J T" uniqKey="Wang J">J.-T. Wang</name>
</author>
<author>
<name sortKey="Lee, C H" uniqKey="Lee C">C.-H. Lee</name>
</author>
<author>
<name sortKey="Wang, J Y" uniqKey="Wang J">J.-Y. Wang</name>
</author>
<author>
<name sortKey="Lee, L N" uniqKey="Lee L">L.-N. Lee</name>
</author>
<author>
<name sortKey="Yu, C J" uniqKey="Yu C">C.-J. Yu</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
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<list>
<country>
<li>Ghana</li>
</country>
</list>
<tree>
<country name="Ghana">
<noRegion>
<name sortKey="Osei, Francis Adjei" sort="Osei, Francis Adjei" uniqKey="Osei F" first="Francis Adjei" last="Osei">Francis Adjei Osei</name>
</noRegion>
<name sortKey="Agyemang, Ebenezer Opambour" sort="Agyemang, Ebenezer Opambour" uniqKey="Agyemang E" first="Ebenezer Opambour" last="Agyemang">Ebenezer Opambour Agyemang</name>
<name sortKey="Amuzu, Evans Xorse" sort="Amuzu, Evans Xorse" uniqKey="Amuzu E" first="Evans Xorse" last="Amuzu">Evans Xorse Amuzu</name>
<name sortKey="Ansong, Daniel" sort="Ansong, Daniel" uniqKey="Ansong D" first="Daniel" last="Ansong">Daniel Ansong</name>
<name sortKey="Ansong, Daniel" sort="Ansong, Daniel" uniqKey="Ansong D" first="Daniel" last="Ansong">Daniel Ansong</name>
<name sortKey="Dekugmen Yar, Denis" sort="Dekugmen Yar, Denis" uniqKey="Dekugmen Yar D" first="Denis" last="Dekugmen Yar">Denis Dekugmen Yar</name>
<name sortKey="Enimil, Anthony" sort="Enimil, Anthony" uniqKey="Enimil A" first="Anthony" last="Enimil">Anthony Enimil</name>
<name sortKey="Laryea, Dennis Odai" sort="Laryea, Dennis Odai" uniqKey="Laryea D" first="Dennis Odai" last="Laryea">Dennis Odai Laryea</name>
<name sortKey="Mensah, Nicholas Karikari" sort="Mensah, Nicholas Karikari" uniqKey="Mensah N" first="Nicholas Karikari" last="Mensah">Nicholas Karikari Mensah</name>
<name sortKey="Nyanor, Isaac" sort="Nyanor, Isaac" uniqKey="Nyanor I" first="Isaac" last="Nyanor">Isaac Nyanor</name>
<name sortKey="Osei, Francis Adjei" sort="Osei, Francis Adjei" uniqKey="Osei F" first="Francis Adjei" last="Osei">Francis Adjei Osei</name>
<name sortKey="Sarpong, Phans Oduro" sort="Sarpong, Phans Oduro" uniqKey="Sarpong P" first="Phans Oduro" last="Sarpong">Phans Oduro Sarpong</name>
</country>
</tree>
</affiliations>
</record>

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